Product Name :
21(S)-Hydroxy Montelukast (CAS 184763-29-9)
Synonym :
[R-[R*,S*-(E)]]-1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid; Montelukast M5a
Application :
21(S)-Hydroxy Montelukast is a montelukast metabolite
CAS:
184763-29-9
Purity:
Molecular Weight:
602.18
Formula :
C35H36ClNO4S
Physical state:
Solid
solubility :
Soluble in acetone, and chloroform.Price of 4-(Vinylsulfonyl)benzoic acid
Shipping Condition :
Store at -20° C
Melting point:
71-75° C
SMILES:
CC(C)(O)C1=C(C=CC=C1)[C@H](O)C[C@@H](SCC1(CC(O)=O)CC1)C1=CC(\\C=C\\C2=NC3=C(C=CC(Cl)=C3)C=C2)=CC=C1
References:
:Montelukast dose selection in 6- to 14-year-olds: comparison of single-dose pharmacokinetics in children and adults.Price of 6-Bromo-2-methylpyrimidin-4-amine | Knorr, B.PMID:33715524 , et al. 1999. J Clin Pharmacol. 39: 786-93. PMID: 10434229In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases. | Cardoso, Jde O., et al. 2015. Drug Metab Dispos. 43: 1905-16. PMID: 26374173Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile. | Balani, SK., et al. 1997. Drug Metab Dispos. 25: 1282-7. PMID: 9351905