Product Name :
YKL-40 / CHI3L1 Mouse Monoclonal Antibody [10C1]
Predicted band size :
Observed band size :
Synonyms:
39 kDa synovial protein antibody ASRT7 antibody Cartilage glycoprotein 39 antibody CGP-39 antibody CGP39 antibody CH3L1_HUMAN antibody CHI3L1 antibody chitinase 3 like 1 (cartilage glycoprotein 39) antibody chitinase 3 like 1 antibody Chitinase 3 like protein 1 precursor antibody 展开
Function :
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance.(Diacetoxyiodo)benzene Order Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.13252-13-6 Price
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within Human YKL-40 aa 24-73 / 383.PMID:33408122
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
10C1
RRID:
AB_3068958
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
43 kDa
Positive control :
THP-1 cell lysates, human tonsil tissue, human liver tissue, mouse lung tissue, HepG2.