Product Name :
TRF1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
hTRF1 AS antibody NIMA interacting protein 2 antibody NIMA-interacting protein 2 antibody PIN 2 antibody PIN2 antibody t TRF1 antibody Telomeric protein Pin2 antibody Telomeric protein Pin2/TRF1 antibody Telomeric repeat binding factor (NIMA interacting) 1 antibody Telomeric repeat binding factor 1 antibody 展开
Function :
Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.878155-85-2 structure
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human TRBF1 121-220/439
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.Methyl 4-bromo-5-methoxypicolinate Chemscene When reconstituted in sterile pH 7.PMID:33392961 4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
50 KDa
Positive control :
Highly expressed and ubiquitous. Isoform Pin2 predominates.