Product Name :
Sodium hydrogen exchanger 1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
amiloride-sensitive antibody APNH antibody APNH1 antibody FLJ42224 antibody Na Li countertransporter antibody Na(+)/H(+) antiporter antibody Na(+)/H(+) exchanger 1 antibody Na+ H+ antiporter amiloride-sensitive antibody Na+ H+ antiporter antibody Na+ H+ exchanger 1 antibody 展开
Function :
The sodium-hydrogen antiporter 1 (NHE-1) also known as sodium/hydrogen exchanger 1 or SLC9A1 (SoLute Carrier family 9A1) is an isoform of sodium–hydrogen antiporter that in humans is encoded by the SLC9A1 gene. The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in volume- and pH-regulation of vertebrate cells.Price of 1206981-68-1 It is inhibited by the non-specific diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others. Sodium–hydrogen antiporter 1 has been shown to interact with carbonic anhydrase II and CHP. It is also the target of the experimental drug rimeporide, which is being developed for the treatment of Duchenne muscular dystrophy.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human NHE1 470-550/815
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.104566-45-2 site When reconstituted in sterile pH 7.PMID:33514882 4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
91 KDa
Positive control :
Kidney and intestine.